Package: scNPM Type: Package Title: Single-Cell Network Propensity Matching Version: 1.1.0 Date: 2026-10-18 Authors@R: c( person( given = "Tao", family = "Liu", email = "25210690190@m.fudan.edu.cn", role = c("aut", "cre") ) ) Description: Estimates and compares heterogeneous gene conditional-dependence networks from single-cell expression data. A latent Gaussian mixture and probit observation mechanism represent cellular heterogeneity and zero observations. Protein interaction information supplies edge-specific prior weights, while network propensity matching links cell clusters across conditions and guides adaptation. Staged inference fixes correspondence after adaptation, disables adaptation feedback, and jointly models matched network edges with a four-state spike-and-slab prior for posterior group and directional differential edge selection. Functions assess balance, record criterion diagnostics, and visualize within-condition and differential networks. License: GPL (>= 3) Encoding: UTF-8 LazyData: true LazyDataCompression: xz Imports: Rcpp (>= 1.0.10), Matrix, igraph (>= 1.3.0), ggplot2 (>= 3.3.0), ggrepel (>= 0.9.0), scales (>= 1.2.0), stats, utils, tools LinkingTo: Rcpp, RcppArmadillo (>= 0.12.6.4.0), RcppParallel (>= 5.1.7) SystemRequirements: C++17, OpenMP Depends: R (>= 4.0.0) URL: https://github.com/taostat1/scNPM_R_package BugReports: https://github.com/taostat1/scNPM_R_package/issues Suggests: testthat (>= 3.0.0) Config/testthat/edition: 3 Config/roxygen2/version: 8.1.0 NeedsCompilation: yes Config/pak/sysreqs: cmake libglpk-dev libxml2-dev Repository: https://taostat1.r-universe.dev Date/Publication: 2026-10-18 10:06:58 UTC RemoteUrl: https://github.com/taostat1/scnpm_r_package RemoteRef: HEAD RemoteSha: 50422755d92ef25c3f9a3c7bf4ced39b21d98271 Packaged: 2026-10-18 11:34:54 UTC; root Author: Tao Liu [aut, cre] Maintainer: Tao Liu <25210690190@m.fudan.edu.cn>